ONCOLOGY MANUFACTURING

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The development of Indian Drugs and pharmaceuticals Industry was not commensurate with the size of this country and the growing needs of people, when Indian embarked on its planned economic expansion industry has been substantial and many sides with the result that it has becomes one of the leading industries. India is now producing a larger quantity of varied pharmaceuticals products.

Oncology is a branch of study and treatment of cancer. Cancer is disease in which abnormal cells grow and divide without control. Oncology drugs help in diagnosis cancer. Some of the causes of cancer are tobacco and smoking, viral infections, genetic causes, carcinogens, bacterial infections, physical activities, eating habits and age.

Various types of cancer that can be treated by oncology drugs are blood cancer, endocrine cancer, lung cancer, bone cancer, skin cancer, genitourinary cancer, gastrointestinal cancer, breast cancer, eye cancer, head and neck cancers and gynaecologic cancer. On the basis of treatment, oncology drugs market can be segmented into chemotherapy, immunotherapy, surgery, radiation therapy, stem cell transplant, hormone therapy and others.

North America, followed by Europe, has the largest market for oncology drugs due to new drug development, government initiatives and developed healthcare infrastructure in this region. Asia is expected to show high growth rate in the oncology drugs market in next few years due to increasing incidence of cancer cases, rise in the use of tobacco products and growth in aging population in the region.

Technological advancement, increasing incidence of various type of cancers, rise in need for R&D activities in cancer and growing concerns over high death rates due to cancer are driving the market for oncology drugs. In addition, introduction of new drugs and therapies for cancer and government support to improve healthcare condition are expected to drive the market for oncology drugs.

However, high cost of cancer treatments, strict government regulations, huge investment involvement in the development and clinical trials of the therapies and side effects of cancer treatments are some of the major factors restraining the growth for global oncology drugs market.

Growing demographics and economies in the developing countries such as China and India are expected to offer good opportunities in oncology drugs market in Asia.

In addition, new innovations in cancer drugs and therapies and rise in awareness about the new drugs and therapies available in the market are expected to offer new opportunities for global oncology drugs market. Personalized medicines, increasing number of mergers and acquisitions, new product launches and rise in number of collaborations and partnerships are some of the trends that have been observed in global oncology drugs market.

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Description

INTRODUCTION
ONCOLOGY AND CRITICAL CARE
ONCOLOGY AND ITS TREATMENT
CHEMOTHERAPY
SOLID TUMORS
FOR LUNG CANCER
FOR ORAL CANCER
FOR COLORECTAL CANCER
FOR PROSTATE
FOR MRCC (MET. RENAL CELL CARCINOMA)
IN WOMEN, THE MOST PREVALENT CANCERS ARE CERVIX, BREAST AND OVARY.
FOR CERVIX CANCERS
FOR BREAST CANCER
IN OVARIAN CANCER
HAEMATOLOGICAL MALIGNANCIES
SUPPORTIVE THERAPY
CRITICALLY ILL PATIENTS
ANTICOAGULANTS
MARKPARIN- ENOXAPARIN (40, 60 MG)
PROPERTIES & CHARACTERISTICS OF INJECTION (DISTILLED WATER)
CHARACTERISTICS OF INJECTABLES:-
USES AND APPLICATIONS
ADVANTAGES OF PARENTERAL PRODUCTS (INJECTABLES):-
OXYTOCIN INJECTION (PITUITARY):-
B.I.S. SPECIFICATION
RAW MATERIALS FOR INJECTION DISTILLED WATER
(DISTILLED WATER AMPOULES)
WATER PROPERTIES
KMNO4 (POTASIUM PERMANGANATE):-
GLASS AMPOULES
INJECTION WATER
SALINE (NORMAL SALINE SOLUTION FOR INJECTION)
ACIDITY OR ALKALINITY:-
BARIUM:-
CALCIUM AND MAGNESIUM:-
HEAVY METALS:-
MARKET OVERVIEW OF ONCOLOGY DRUGS
THE ONCOLOGY DRUGS MARKET IS SEGMENTED BY TYPE INTO
THE ONCOLOGY DRUGS MARKET IS SEGMENTED BY DRUG CLASS TYPE INTO
THE ONCOLOGY DRUGS MARKET IS SEGMENTED BY DISTRIBUTION CHANNEL INTO
THE ONCOLOGY DRUGS MARKET IS SEGMENTED BY ROUTE OF ADMINISTRATION INTO
THE ONCOLOGY DRUGS MARKET IS SEGMENTED BY DRUG CLASSIFICATION INTO
PRIME COMPETITORS IN THIS ONCOLOGY DRUGS MARKET ARE AS FOLLOWS:
SOME OTHER PROMINENT COMPETITORS ARE AS FOLLOWS:
FUTURE OF ONCOLOGY DRUGS
ONCOLOGY DRUG MARKET IN INDIA
FINDINGS FROM A STUDY CONCLUDED THE CANCER SCENARIO IN INDIA THAT:
MARKET SIZE
S.W.O.T. ANALYSIS
STRENGTHS
WEAKNESS
OPPORTUNITIES
INDUSTRY CHALLENGES
LATEST DEVELOPMENTS IN INDIAN ONCOLOGY DEPARTMENT
CIPLA:
ZYDUS CADILA:
BIOCON LTD.:
NEW PLAYERS IN THE INDIAN ONCOLOGY MARKET
AUROBINDO PHARMA LTD.:
ALEMBIC PHARMA LTD.:
GLOBAL ONCOLOGY MARKET AND PROCESS SOLUTION
ONCOLOGY AND ITS TREATMENT
CHEMOTHERAPY
GENERIC DRUGS IN ONCOLOGY
MANUFACTURING PROCESS OF INJECTION WATER
FILLING OF AMPOULES
PROCESS FLOW CHART
PROCESSING OF PARENTRAL PRODUCTS INJECTIONS
1. ENVIRONMENTAL CONTROL:-
TECHNIQUES INVOLVED IN THE PREPARATION OF INJECTABLES
PACKING OF PARENTERAL PRODUCTS (PACKING OF INJECTABLES)
PROCESSING OF CONTAINES & CLOSURES:-
EVALUATION OF PARENTERAL PRODUCTS
A. STERILITY TEST:-
PYROGEN TEST:-
CLARITY TESTS:-
LEAKAGE TESTS:-
FLOW DIAGRAM FOR PREPARATION OF INJECTABLES
MANUFACTURING PROCESS OF INJECTIONS
MANUFACTURING PROCESS OF TABLETS
FLOW DIAGRAM OF TABLET MAKING PLANT
CAPSULE FILLING AND SEALING
(A) DILUENTS:
(B) PROTECTIVE SORBENTS:
(C) GLIDANTS:
(D) ANTI-DUSTING COMPOUNDS:
FILLING:
SEALING AND LOCKING:
FLOW DIAGRAM OF CAPSULE MAKING PLANT
ONCOLOGY DRUGS
FORMULATION OF LETROZOLE TABLETS
FORMULATION OF ENZALUTAMIDE CAPSULES
FORMULATION OF TEMOZOLOMIDE CAPSULE
ADVANCED COLORECTAL CANCER
ADJUVANT TREATMENT OF COLORECTAL CANCER
ADVERSE EFFECTS
DOSAGE AND ADMINISTRATION
DOSAGE
PRINCIPLES OF PLANT LAYOUT
MAJOR PROVISIONS IN ROAD PLANNING FOR MULTIPURPOSE SERVICE ARE:
PLANT LOCATION FACTORS
PRIMARY FACTORS
1. RAW-MATERIAL SUPPLY:
2. MARKETS:
3. POWER AND FUEL SUPPLY:
4. WATER SUPPLY:
5. CLIMATE:
6. TRANSPORTATION:
7. WASTE DISPOSAL:
8. LABOR:
9. REGULATORY LAWS:
10. TAXES:
11. SITE CHARACTERISTICS:
12. COMMUNITY FACTORS:
13. VULNERABILITY TO WARTIME ATTACK:
14. FLOOD AND FIRE CONTROL:
EXPLANATION OF TERMS USED IN THE PROJECT REPORT
1. DEPRECIATION:
2. FIXED ASSETS:
3. WORKING CAPITAL:
4. BREAK-EVEN POINT:
5. OTHER FIXED EXPENSES:
6. MARGIN MONEY:
7. TOTAL LOAD:
8. LAND AREA/MAN POWER RATIO:
PROJECT IMPLEMENTATION SCHEDULES
INTRODUCTION
PROJECT HANDLING
PROJECT SCHEDULING
PROJECT CONSTRUCTION SCHEDULE
TIME SCHEDULE
SUPPLIERS OF PHARMACEUTICAL PLANTS AND MACHINERY
SUPPLIERS OF RAW MATERIALS

APPENDIX – A:

01. PLANT ECONOMICS
02. LAND & BUILDING
03. PLANT AND MACHINERY
04. OTHER FIXED ASSESTS
05. FIXED CAPITAL
06. RAW MATERIAL
07. SALARY AND WAGES
08. UTILITIES AND OVERHEADS
09. TOTAL WORKING CAPITAL
10. TOTAL CAPITAL INVESTMENT
11. COST OF PRODUCTION
12. TURN OVER/ANNUM
13. BREAK EVEN POINT
14. RESOURCES FOR FINANCE
15. INSTALMENT PAYABLE IN 5 YEARS
16. DEPRECIATION CHART FOR 5 YEARS
17. PROFIT ANALYSIS FOR 5 YEARS
18. PROJECTED BALANCE SHEET FOR (5 YEARS)

Additional information

Plant Capacity

270000 Nos/Day
Land & Building

(6000 sq.mt.)
Plant & Machinery

US$ 835714
Rate of Return

47%
Break Even Point

32%

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