PAPAIN ENZYME MANUFACTURING PLANT 100 TPA (REFINED PAPAIN)

Papaya is a versatile plant having number of uses and enzymatic properties. It could also be called medical plant rendering high income to farmers. One can manufacture products like tutti-frutti, candy slices (murabba) and dehydrated papaya powder from raw papaya.

Origin of Papaya

Though the exact area of origin is unknown, papaya is believed to be a native to tropical America, perhaps in southern Mexico and neighbouring Central America. It is recorded that seeds were taken to Panama and then the Dominican Republic before 1525 and cultivation spread to warm elevations throughout South and Central America, southern Mexico, the West Indies and Bahamas and to Bermuda in 1616. Spaniards carried seeds to the Philippines about the year 1550 and the papaya traveled from there to Malacca and India. Seeds were sent from India to Naples in 1626. Now the papaya is familiar in nearly all tropical regions of the Old World and the Pacific Islands and has become naturalized in many areas. Seeds were probably brought to Florida from the Bahamas. Up to about 1959, the papaya was commonly grown in southern and central Florida in home gardens and on a small commercial scale. Thereafter, natural enemies seriously reduced the plantings.

The latex of the papaya plant and its green fruits contains two proteolytic enzymes, papain and chymopapain. The latter is most abundant but papain is twice as potent. In 1933, Ceylon (Sri Lanka) was the leading commercial source of papain but it has been surpassed by East Africa where large-scale production began in 1937.

Papain Papain is the only plant proteinase now being used as a protein digestant. It is used in combating dyspepsia and other digestive disorders. It is used in the manufacturer of pharmaceutical preperations like glyc. Papain, elix papain, liquid papain and liver tonics. Papain finds extensive use in the manufacturer of proteolysed preperations of meat, liver and casein. In brewing industries it is also used in tenderizing meat and softening of leathers, degumming of natural silk and wool fabrics, chewing gums, tooth paste and cosmetics. Indigenous demand its 80-90% production is exported to USA and European countries, Western countries import purified papaya latex for further processing to meet their specialised needs.

INTRODUCTION
PROPERTIES
ENZYME & ITS CLASSIFICATION
B.I.S. SPECIFICATION & ITS REQUIREMENTS
USES & APPLICATION
USES AND APPLICATION OF REFINED PAPAIN
MARKET SURVEY
PRODUCTION OF PAPAYA
INSTALLED CAPACITY, PRODUCTION & CAPACITY UTILIZATION OF PAPAIN
APPARENT CONSUMPTION OF PAPAIN
ESTIMATED DEMAND
EXPORT DATA OF PAPAIN
IMPORT DATA OF PAPAIN
INDIAN ENZYME MARKET
MANUFACTURERS AND EXPORTERS OF PAPAIN
LIST OF BUYERS
MEDICINES MANUFACTURERS (BUYERS OF PAPAIN)
MANUFACTURING PROCESS OF REFINED PAPAIN
PROCESS IN DETAILS
PROCESS FLOW DIAGRAM
METHODS OF COLLECTION AND EXTRACTION
PROCESS OF MANUFACTURE
PROCESS FLOW DIAGRAM
MANUFACTURING PROCESS OF IP GRADE PAPAIN & PAPAIN CONCENTRATE
MANUFACTURING PROCESS OF CRUDE PAPAIN
EVALUATION OF DRYING TECHNIQUE MEASURING PROTEOLYTIE ACTIVITY OF PAPAIN OBTAINED FROM UNRIPE FRUIT AND SKIN JUICE
PRINCIPLES OF PLANT LAYOUT
PLANT LOCATION FACTORS
EXPLANATION OF TERMS USED IN THE PROJECT REPORT
PROJECT IMPLEMENTATION SCHEDULES
PLANT LAYOUT
TECHNICAL KNOW HOW AND TECHNOLOGY SUPPLIER FOR PAPAIN
SUPPLIER OF RAW MATERIALS
SUPPLIERS OF EXTRACTION PLANTS & MACHINERY
INSTRUMENTATION AND PROCESS CONTROL EQUIPMENT

APPENDIX – A :

1. COST OF PLANT ECONOMICS
2. LAND & BUILDING
3. PLANT AND MACHINERY
4. FIXED CAPITAL INVESTMENT
5. RAW MATERIAL
6. SALARY AND WAGES
7. UTILITIES AND OVERHEADS
8. TOTAL WORKING CAPITAL
9. COST OF PRODUCTION
10. PROFITABILITY ANALYSIS
11. BREAK EVEN POINT
12. RESOURCES OF FINANCE
13. INTEREST CHART
14. DEPRECIATION CHART
15. CASH FLOW STATEMENT
16. PROJECTED BALANCE SHEET